刘小龙
刘小龙
更新日期:2018-09-20  

  刘小龙,研究员、博士生导师。曾长期留学于美国布朗大学和瑞士巴塞尔大学。主要从事肿瘤早期诊断新技术与新方法、免疫治疗与精准医学方面的基础与临床转化研究。现主持国家自然科学基金国家重大科研仪器研制项目”、国家自然科学基金重点项目等省部级科研项目15项;在国际知名期刊上发表SCI收录论文70多篇,授权国家发明专利20项。曾荣获德国洪堡学者奖学金,日本肿瘤学会青年科学家奖,“福建青年五四奖章标兵”、“福建青年科技奖”,福州市劳动模范等荣誉。   

  电话: 0591-83705927  邮箱:liuxl@fjirsm.ac.cn 

  地址: 福建省福州市西洪路312号福建医科大学孟超肝胆医院 

  研究方向:肿瘤学、精准医学、肿瘤诊疗新技术 

  代表性论文: 

  1.D Zhang, Z Cai, N Liao, S Lan, M Wu, H Sun, Z Wei, J Li*, and X Liu*. pH / Hypoxia Programmable Triggered Cancer Photo-Chemotherapy Based on Semiconducting Polymer dot hybridized Mesoporous Silica Framework. Chemical Science, 2018, DOI: 10.1039/c8sc02408a. 

  2.X Lin#, M Wu#, M Li, Z Cai, H Sun, X Tan, J Li, Y Zeng, X Liu*, and J Liu*. Photo-responsive hollow silica nanoparticle for light triggered genetic and photodynamic synergistic therapy. Acta Biomaterialia, 2018, 76:178-192.  

  3.X Zhang, M Wu, J Li, S Lan, Y Zeng, X Liu*, and J Liu*. Light-Enhanced Hypoxia-Response of Conjugated Polymer Nanocarrier for Successive Synergistic Photodynamic and Chemo-Therapy. ACS Applied Materials and Interfaces, 2018, 10: 21909-21919. 

  4.J Li, X Wang, D Zheng, X Lin, Z Wei, D Zhang, Z Li, Y Zhang, M Wu*, and X Liu*. Cancer cell membrane-coated magnetic nanoparticles for MR/NIR fluorescence dual-modal imaging and photodynamic therapy. Biomaterials Science, 2018, 6(7):1834-1845. 

  5.M Li#, X Wu #, J Gao, F Yang, C Zhang, K Ke, Y Wang, Y Zheng, J Yao, Y Guan, X Chen, J Chen, X Liu*, and X Yang*. Mutations in the P10 region of procaspase-8 lead to chemotherapy resistance in acute myeloid leukemia by impairing procaspase-8 dimerization. Cell Death & Disease, 2018, 9:516, DOI: 10.1038/s41419-018-0511-3. 

  6.D Zhang, M Wu, Z Cai, N Liao, K Ke, H Liu, M Li, G Liu, H Yang, X Liu*, and J Liu*. FDA approved drug based metal-organic particles for microvesicle-mediated deep penetration and pH / NIR / hypoixa-programmable activated cancer photo-chemotherapy. Advanced Science, 2018, 5(2):1700648, DOI: 10.1002/advs.201700648. 

  7.C Yao#, J Wang#, A Zheng, L Wu, X Zhang*, and X Liu*. A fluorescence sensing platform with the MnO2 nanosheets as an effective oxidant for glutathione detection. Sensors and Actuators B-Chemical, 2017, 252: 30-36. 

  8.D Zhang, A Zheng, J Li, M Wu, L Wu, Z Wei, N Liao, X Zhang, Z Cai, H Yang, X Liu*, and J Liu*. Smart Cu(II)-aptamer complexes based gold nanoplatform for tumor micro-environment triggered programmable intracellular prodrug release, photodynamic treatment and aggregation induced photothermal therapy in hepatocellular carcinoma. Theranostics, 2017, 7(1): 164-179. 

  9.Y Zeng#, A Zheng#, J Wu, Z Cai, A Huang*, and X Liu*. Horseradish peroxidase and aptamer dual-functionalized nanoprobe for the amplification detection of alpha-methylacyl-CoA racemase. Analytica Chimica Acta., 2015, 899:100-5.  

  10.Y Zeng, D Zhang, M Wu, Y Liu, X Zhang, L Li, Z Li, X Han, X Wei, X Liu*. Lipid-AuNPs@Polydopamine Nanohybirds for targeted MRI/CT dual-mode image guide photo thermo therapy of hepatocellular carcinioma. ACS Applied materials and interfaces, 2014, 6(16): 14266-77.